If both patients have anatomical dead space of 200 m l, who has better alveolar ventilation?3/2/2024 VA = f (VT – Vd) OR where alveolar ventilation = minute ventilation – dead space. The PCO 2 equation states that alveolar PCO 2 is directly proportional to the amount of CO 2 produced by metabolism and delivered to the lungs (VCO2) and is inversely proportional to alveolar ventilation (VA) o □□□□□ = □□□□ □ □.□□□ □□ which is derived from □□ = □□□□ □ □.□□□ □□□□□ where alveolar ventilation = respiratory frequency x (tidal volume – dead space). where barometric pressure (PB) at sea level is 760 mmHg where water vapor pressure at body temp is 47 mmHg o PACO 2 = alveolar partial pressure of CO 2 o R = respiratory exchange ratio ie CO 2 released/O 2 absorbed during respiration in the lungs = 200/250 = 0. RER = 0 (VCO2 = 200/VO2 = 250) RQ = 0 (mixed diet) Hematocrit = 0/45% Hemoglobin = 15 g/dL (13-18) PB = 760 mmHg (sea level) FIO 2 = 0.209/20% Water vapor constant = 47 mmHg Respiratory acidosis Metabolic acidosis Respiratory alkalosis Metabolic alkalosis Compensated? (c) ↓ ↓ ↑ ↑ ↑ ↓(c) ↓ ↑(c) ↑(c) ↓ ↓(c) ↑ Dissolved O 2 in arterial plasma where PaO 2 = 100mg is 0 mL O 2 /dl blood Dissolved CO 2 in arterial blood where PaCO 2 = 100 mg is 7 mL CO 2 /dl blood Chemoreceptor PaO 2 response: 60 mmHg Alveolar Gas Equation o □□□□ = □□□□ − □□□□□ □. PaCO 2 = 35-45 mmHg = 24 mM Anion gap = 9-13 mEq/L Inspired air sea level (PIO 2 /PICO 2 ) Alveolar air (PAO 2 /PACO 2 ) Arterial blood (PaO 2 /PaCO 2 ) Mixed venous blood (PvO 2 /PvCO 2 ) 149 100 80- 40 0 40 40 45 Acid-Base Disorders pH PaCO 2 V/Q = 0. NORMAL VALUES and KEY EQUATIONS Renal Review Location O 2 - mmHg CO 2 - mmHg pH: 7-7.
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